Toxicology Calculator
Run validated toxicology calculations with full audit trails
ELCR (CSF)
Excess Lifetime Cancer Risk — Oral
EPA cancer risk using oral Cancer Slope Factor.
ELCR = CDI × CSF
ELCR (IUR)
Excess Lifetime Cancer Risk — Inhalation
EPA cancer risk using Inhalation Unit Risk.
ELCR = Air Conc × IUR
MOE
Margin of Exposure
Point of Departure divided by estimated human exposure.
MOE = POD / Exposure
MOS
Margin of Safety
Acceptable Daily Exposure divided by estimated daily exposure.
MOS = ADE / Daily Exposure
RfD
Reference Dose
Derives oral Reference Dose from NOAEL and uncertainty factors.
RfD = NOAEL / (UF1 × UF2 × ... × UFn)
TTC
TTC Threshold
Returns TTC threshold. Optionally compares to measured exposure.
TTC from Cramer class (I/II/III/genotoxic)
Unit Converter
Dose Unit Converter
General-purpose dose unit conversion with body weight normalization.
Converts between mg/kg-day, ug/kg-day, mg/day, ppm, ppb